Doctors Cure Man Of Diabetes

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Doctors Cure Man Of Diabetes

March 10, 2005

Doctors at King's College Hospital, London, have successfully cured a man of Type 1 diabetes by injecting pancreatic cells into his liver.

The patient, a 61 year old man, now no longer needs insulin injections, following three transplants of islet cells isolated from cadaveric donor pancreases. This breakthrough has major implications for diabetes sufferers and has never before been achieved in the United Kingdom.

This patient has proved that it is possible for islet transplants to lead to freedom from administered insulin and diabetes treatment associated problems.

The patient suffered from Type 1 diabetes for over 30 years, experiencing increasing problems with his diabetes therapy. Prior to the islet transplant he endured severe, potentially life threatening hypoglycaemic attacks, which profoundly affected his quality of life. Following the islet transplant he is now producing his own insulin and is completely free from hypoglycaemia.

The King’s team, a collaboration between the Department of Diabetes and the Liver Unit’s transplantation team, has to date transplanted three Type 1 diabetes patients with pancreatic islet cells. The first two patients achieved partial success, achieving relief of hypoglycaemia problems, but still requiring small doses of insulin.

Islet cells are obtained from donor pancreases and are transplanted by injection, into the liver of the recipient. Once in the liver, the cells develop their own blood supply and begin producing insulin. This procedure is minimally invasive and only takes around 45 minutes to complete.
Doctors Cure Man Of Diabetes